Journal of Endodontics
Volume 32, Issue 2 , Pages 87-92 , February 2006

A Cochrane Systematic Review Finds No Evidence to Support the Use of Antibiotics for Pain Relief in Irreversible Pulpitis

  • James V. Keenan, DDS (FAGD)

      Affiliations

    • U.S. Naval Health Clinics, United Kingdom
    • ,
  • Allan G. Farman, BDS, PhD, DSc

      Affiliations

    • Surgical and Hospital Dentistry, The University of Louisville, Louisville, Kentucky
    • ,
  • Zbigniew Fedorowicz, BDS, LDS, RCS (Eng)

      Affiliations

    • UK Cochrane Centre (Bahrain Branch), The Cochrane Collaboration
    • Corresponding Author InformationAddress requests for reprints to Dr. Zbigniew Fedorowicz, Box 25438, Awali, Bahrain.
    • ,
  • Jonathan T. Newton, BA, PhD

      Affiliations

    • GKT Dental Institute, King’s College London, Kings College Hospital, London.

References 

  1. Lipton JA , Ship JA , Larach-Robinson D . Estimated prevalence and distribution of reported orofacial pain in the United States . JADA . 1993;124:115–121
  2. Bergenholtz G . Pathogenic mechanisms in pulpal disease . J Endod . 1990;16:98–101
  3. Hahn CL , Falkler WA , Minah GE . Microbiological studies of carious dentine from human teeth with irreversible pulpitis . Arch Oral Biol . 1991;36:147–153
  4. Tronstad L . The endodontium . In: Clinical endodontics . New York: Thieme; 1991;p. 1–31
  5. Nagle D , Reader A , Beck M , Weaver J . Effect of systemic penicillin on pain in untreated irreversible pulpitis . Oral Surg Oral Med Oral Pathol Oral Radio Endod . 2000;90:636–640
  6. Soames JV , Southam JC . Oral pathology . 3rd ed.. Oxford: Oxford University Press; 1998;
  7. Cecic PA , Hartwell GR , Belizzi R . Cold as a diagnostic aid in cases of irreversible pulpitis. Report of two cases . Oral Surg Oral Med Oral Pathol . 1983;56:647–650
  8. Oguntebi BR , DeSchepper EJ , Taylor TS , White CL , Pink FE . Postoperative pain incidence related to the type of emergency treatment of symptomatic pulpitis . Oral Surg Oral Med Oral Pathol . 1992;73:479–483
  9. Yingling NM , Byrne BE , Hartwell GR . Antibiotic use by members of the American Association of Endodontists in the year 2000 (report of a national survey) . J Endod . 2002;28:396–404
  10. Fouad AF , Rivera EM , Walton RE . Penicillin as a supplement in resolving the localized acute apical abscess . Oral Surg Oral Med Oral Pathol Oral Radiol Endod . 1996;81:590–595
  11. Clarke M, Oxman AD, eds. Cochrane Reviewers’ Handbook 4.2.0 [updated March 2003]. In: The Cochrane Database of Systematic Reviews, Issue 2, 2003.
  12. Matthews DC , Sutherland S , Basrani B . Emergency management of acute apical abscesses in the permanent dentition (a systematic review of the literature) . J Canad Dent Assoc . 2003;69:660
  13. Henry M , Reader A , Beck M . Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth . J Endod . 2001;27:117–123
  14. Nusstein JM , Beck M . Comparison of preoperative pain and medication use in emergency patients presenting with irreversible pulpitis or teeth with necrotic pulps . Oral Surg Oral Med Oral Pathol Oral Radiol Endod . 2003;96:207–214
  15. Heft MW , Parker SR . An experimental basis for revising the graphic rating scale for pain . Pain . 1984;19:153–161

PII: S0099-2399(05)00069-5

doi: 10.1016/j.joen.2005.10.029

Journal of Endodontics
Volume 32, Issue 2 , Pages 87-92 , February 2006

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