Journal of Endodontics
Volume 32, Issue 2 , Pages 99-103 , February 2006

Pulpal Inflammation and Incidence of Coronary Heart Disease

  • Kaumudi J. Joshipura, ScD

      Affiliations

    • Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, Massachusetts
    • Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts
    • Division of Dental Public Health, University of Puerto Rico School of Dentistry, San Juan, Puerto Rico
    • Corresponding Author InformationAddress requests for reprint to Dr. Kaumudi Joshipura, Department of Oral Health Policy & Epidemiology, Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA 02115.
    • ,
  • Waranuch Pitiphat, ScD

      Affiliations

    • Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, Massachusetts
    • Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts
    • Department of Community Dentistry, Khon Kaen University, Thailand
    • ,
  • Hsin-Chia Hung, ScD

      Affiliations

    • Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts
    • Institute of Health Care Management, National Sun Yat-sen University, Taiwan
    • ,
  • Walter C. Willett, DrPH

      Affiliations

    • Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts
    • Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts.
    • Channing Laboratory and the Division of Preventive Medicine, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, Massachusetts.
    • ,
  • Graham A. Colditz, ScD

      Affiliations

    • Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts
    • Channing Laboratory and the Division of Preventive Medicine, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, Massachusetts.
    • ,
  • Chester W. Douglass, PhD

      Affiliations

    • Department of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, Massachusetts
    • Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts

References 

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  2. DeStefano F , Anda RF , Kahn HS , Williamson DF , Russell CM . Dental disease and risk of coronary heart disease and mortality . BMJ . 1993;306:688–691
  3. Joshipura KJ , Douglass CW , Willett WC . Possible explanations for the tooth loss and cardiovascular disease relationship . Ann Periodontol . 1998;3:175–183
  4. Mattila KJ , Nieminen MS , Valtonen VV , et al.   Association between dental health and acute myocardial infarction . [see comments] BMJ . 1989;298:779–781
  5. Grau AJ , Buggle F , Ziegler C , et al.   Association between acute cerebrovascular ischemia and chronic and recurrent infection . Stroke . 1997;28:1724–1729
  6. Jansson L , Lavstedt S , Frithiof L , Theobald H . Relationship between oral health and mortality in cardiovascular diseases . J Clin Periodontol . 2001;28:762–768
  7. Frisk F , Hakeberg M , Ahlqwist M , Bengtsson C . Endodontic variables and coronary heart disease . Acta Odontol Scand . 2003;61:257–262
  8. Grossman L . Evaluation of antibiotic agents for root canal treatment . NY J Dent . 1945;15:233–245
  9. Auerbach M . Antibiotics vs. instrumentation in endodontics . N Y State Dental J . 1953;19:225–228
  10. Rimm EB , Stampfer MJ , Colditz GA , Giovannucci E , Willett WC . Effectiveness of various mailing strategies among nonrespondents in a prospective cohort study . Am J Epidemiol . 1990;131:1068–1071
  11. Rose GA , Blackburn H . Cardiovascular Survey Methods . In: World Health Organization; 1982;p. 58; WHO Monograph Series
  12. Pitiphat W , Garcia RI , Douglass CW , Joshipura KJ . Validation of self-reported oral health measures . J Public Health Dent . 2002;62:122–128
  13. Boykin MJ , Gilbert GH , Tilashalski KR , Shelton BJ . Incidence of endodontic treatment (a 48-month prospective study) . J Endod . 2003;29:806–809
  14. Caplan DJ , Pankow J , Cai J , Offenbacher S , Beck J . Endodontic infection and coronary heart disease in the ARIC study . IADR; 2002;
  15. Caplan DJ . Lesions of endodontic origin and risk of coronary heart disease . J Dent Res . 2004; Abstract No. 1323
  16. Tilashalski KR , Gilbert GH , Boykin MJ , Shelton BJ . Root canal treatment in a population-based adult sample (status of teeth after endodontic treatment) . J Endod . 2004;30:577–581
  17. Sundqvist G . Taxonomy, ecology, and pathogenicity of the root canal flora . Oral Surg Oral Med Oral Pathol . 1994;78:522–530
  18. Bergenholtz G . Micro-organisms from necrotic pulp of traumatized teeth . Odontol Revy . 1974;25:347–358
  19. Murray C , Saunders W . Root canal treatment and general health (a review of the literature) . Int Endod J . 2000;33:1–18

PII: S0099-2399(05)00079-8

doi: 10.1016/j.joen.2005.10.039

Journal of Endodontics
Volume 32, Issue 2 , Pages 99-103 , February 2006

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