Journal of Endodontics
Volume 32, Issue 2 , Pages 93-98 , February 2006

Enterococcus faecalis: Its Role in Root Canal Treatment Failure and Current Concepts in Retreatment

References 

  1. Evans M , Davies JK , Sundqvist G , Figdor D . Mechanisms involved in the resistance of Enterococcus faecalis to calcium hydroxide . Int Endod J . 2002;35:221–228
  2. Baumgartner JC , Falkler WA . Bacteria in the apical 5 mm of infected root canals . J Endod . 1991;17:380–383
  3. Molander A , Reit C , Dahlen G , Kvist T . Microbiological status of root-filled teeth with apical periodontitis . Int Endod J . 1998;31:1–7
  4. Sundqvist G , Figdor D , Persson S , Sjogren U . Microbiologic analysis of teeth with failed endodontic treatment and the outcome of conservative re-treatment . Oral Surg Oral Med Oral Pathol Oral Radiol Endod . 1998;85:86–93
  5. Hancock HH , Sigurdsson A , Trope M , Moiseiwitsch J . Bacteria isolated after unsuccessful endodontic treatment in a North Am population . Oral Surg Oral Med Oral Pathol Oral Radiol Endod . 2001;91:579–586
  6. Gilmore MS . The Enterococci (pathogenesis, molecular biology, and antibiotic resistance) . Washington: ASM Press; 2002;
  7. Rôças IN , Siqueira JF , Santos KRN . Association of Enterococcus faecalis with different forms of periradicular diseases . J Endod . 2004;30:315–320
  8. Koch S , Hufnagel M , Theilacker C , Huebner J . Enterococcal infections (host response, therapeutic, and prophylactic possibilities) . Vaccine . 2004;22:822–830
  9. Tendolkar PM , Baghdayan AS , Shankar N . Pathogenic Enterococci (new developments in the 21st century) . Cell Mol Life Sci . 2003;60:2622–2636
  10. Teixeira LM , Facklam RR . Enterococcus . In:  Murray PR editors. Manual of clinical microbiology . 8th ed.. Washington: ASM Press; 2003;p. 422–433
  11. Facklam RR , Carvalho MGS , Teixeira LM . History, taxonomy, biochemical characteristics, and antibiotic susceptibility testing of Enterococci . In:  Gilmore MS editors. The Enterococci (pathogenesis, molecular biology, and antibiotic resistance) . Washington: ASM Press; 2002;p. 1–54
  12. Dautle MP , Ulrich RL , Hughes TA . Typing and subtyping of 83 clinical isolates purified from surgically implanted silicone feeding tubes by random amplified polymorphic DNA amplification . J Clin Microbiol . 2002;40:414–421
  13. Mato R , de Lencastre H , Roberts RB , Tomasz A . Multiplicity of genetic backgrounds among vancomycin-resistant Enterococcus faecium isolates recovered from an outbreak in a New York City hospital . Microb Drug Resist . 1996;2:309–317
  14. http://www.atcc.org/common/catalog/bacteria/bacteriaIndex.cfm. Accessed May 25, 2005.
  15. Jett BD , Huycke MM , Gilmore MS . Virulence of Enterococci . Clin Microbiol Rev . 1994;7:462–478
  16. Nallapareddy SR , Duh RW , Singh KV , Murray BE . Molecular typing of selected Enterococcus faecalis isolates (pilot study using multilocus sequence typing and pulse-field gel electrophoresis) . J Clin Microbiol . 2002;40:868–876
  17. Franz CM , Stiles ME , Schleifer KH , Holzapfel WH . Enterococci in foods (a conundrum for food safety) . Int J Food Microbiol . 2003;88:105–122
  18. Ribeiro Sobrinho AP , Barros MHM , Nicoli JR . Experimental root canal infections in conventional and germ-free mice . J Endod . 1998;24:405–408
  19. de Melo Maltos SM , Ribeiro Sobrinho AP , Silva FV , et al.   Bacterial concentrations determine the ability to implant in the root canal system and translocate to lymph nodes in germ-free mice . J Endod . 2003;29:24–27
  20. Murray BE . The life and times of Enterococcus . Clin Microbiol Rev . 1990;3:46–65
  21. Edmond MB , Ober JF , Dawson JD , Weinbaum DL , Wenzel RP . Vancomycin-resistant enterococcal bacteremia (natural history and attributable mortality) . Clin Infect Dis . 1996;23:1234–1239
  22. Novias C , Vital C , Ribeiro G , Coque TM , Peixe LV . First characterization of vancomycin-resistant Enterococci from a Portuguese hospital . J Antimicrob Chemother . 2002;49:215–217
  23. Sedgley CM , Lennan SL , Clewell DB . Prevalence, phenotype, and genotype of oral Enterococci . Oral Microbiol Immunol . 2004;19:95–101
  24. Engström B . The significance of Enterococci in root canal treatment . Odontol Revy . 1964;15:87–106
  25. Möller AJR. Microbial examination of root canals and periapical tissues of human teeth . Odontol Tidskr . 1966;74(Suppl):1–380
  26. Peciuliene V , Balciuniene I , Eriksen H , Haapasalo M . Isolation of Enterococcus faecalis in previously root-filled canals in a Lithuanian population . J Endod . 2000;26:593–595
  27. Peciuliene V , Reynaud AH , Balciuniene I , Haapasalo M . Isolation of yeasts and enteric bacteria in root-filled teeth with chronic apical periodontitis . Int Endod J . 2001;34:429–434
  28. Pinheiro ET , Gomes BPFA , Ferraz CCR , Sousa ELR , Teixeira FB , Souza Filho FJ . Microorganisms from canals of root-filled teeth with periapical lesions . Int Endod J . 2003;36:1–11
  29. Pinheiro ET , Gomes BPFA , Ferraz CCR , Teixeira FB , Zaia AA , Souza-Filho FJ . Evaluation of root canal microorganisms isolated from teeth with endodontic failure and their antimicrobial susceptibility . Oral Microbiol Immunol . 2003;18:100–103
  30. Siqueira JF , Rôças I . Polymerase chain reaction-based analysis of microorganisms associated with failed endodontic treatment . Oral Surg Oral Med Oral Pathol Oral Radiol Endod . 2004;97:85–94
  31. Gomes BPFA , Pinheiro ET , Gade-Neto CR , et al.   Microbiological examination of infected dental root canals . Oral Microbiol Immunol . 2004;19:71–76
  32. Fouad AF , Zerella J , Barry J , Spangberg LS . Molecular detection of Enterococcus species in root canals of therapy-resistant endodontic infections . Oral Surg Oral Med Oral Pathol Oral Radiol Endod . 2005;99:112–118
  33. Baumgartner JC , Siqueira JF , Xia T , Rôças IN . Geographical differences in bacteria detected in endodontic infections using polymerase chain reaction . J Endod . 2004;30:141–144
  34. Molander A , Lundquist P , Papapanou PN , Dahlen G , Reit C . A protocol for polymerase chain reaction detection of Enterococcus faecium from the root canal . Int Endod J . 2002;35:1–6
  35. Siqueira JF , Rocas IN . PCR methodology as a valuable tool for identification of endodontic pathogens . J Dent . 2003;31:333–339
  36. Kishen A , Chen NN , Tan L , Asundi A . Chairside sensor for rapid monitoring of Enterococcus faecalis activity . J Endod . 2004;30:872–875
  37. Love RM . Enterococcus faecalis (a mechanism for its role in endodontic failure) . Int Endod J . 2001;34:399–405
  38. Lee W , Lim S , Son H , Bae K . Sonicated extract of Enterococcus faecalis induces irreversible cell cycle arrest in phytohemagglutinin-activated human lymphocytes . J Endod . 2004;30:209–212
  39. Hubble TS , Hatton JF , Nallapareddy SR , Murray BE , Gillespie MJ . Influence of Enteroccocus faecalis proteases and the collagen-binding protein, Ace, on adhesion to dentin . Oral Microbiol Immunol . 2003;18:121–126
  40. Figdor D , Davies JK , Sundqvist G . Starvation survival, growth and recovery of Enterococcus faecalis in human serum . Oral Microbiol Immunol . 2003;18:234–239
  41. Orstavik D , Haapasalo M . Disinfection by endodontic irrigants and dressings of experimentally infected dentinal tubules . Endod Dent Traumatol . 1990;6:142–149
  42. Haapasalo M , Orstavik D . In vitro infection and disinfection of dentinal tubules . J Dent Res . 1987;66:1375–1379
  43. Distel JW , Hatton JF , Gillespie MJ . Biofilm formation in medicated root canals . J Endod . 2002;28:689–693
  44. Lin Y , Mickel A , Chogle S . Effectiveness of selected materials against Enterococcus faecalis: Part 3. The antibacterial effect of calcium hydroxide and chlorhexidine on Enterococcus faecalis . J Endod . 2003;29:565–566
  45. McHugh CP , Zhang P , Michalek S , Eleazer PD . pH required to kill Enterococcus faecalis in vitro . J Endod . 2004;30:218–219
  46. Tronstad L , Andreasen J , Hasselgren G , Kristerson L , Riis I . pH changes in dental tissues after root filling with calcium hydroxide . J Endod . 1981;7:17–21
  47. Haapasalo HK , Siren EK , Waltimo TMT , Orstavik D , Haapasalo MPP . Inactivation of local root canal medicaments by dentine (an in vitro study) . Int Endod J . 2000;33:126–131
  48. Portenier I , Haapasalo H , Rye A , Waltimo T , Orstavik D , Haapasalo M . Inactivation of root canal medicaments by dentine, hydroxylapatite and bovine serum albumin . Int Endod J . 2001;34:184–188
  49. Portenier I , Haapasalo H , Orstavik D , Yamauchi M , Haapasalo M . Inactivation of the antibacterial activity of iodide potassium iodide and chlorhexidine digluconate against Enterococcus faecalis by dentin, dentin matrix, type-I collagen, and heat-killed microbial whole cells . J Endod . 2002;28:634–637
  50. Card SJ , Sigurdsson A , Orstavik D , Trope M . The effectiveness of increased apical enlargement in reducing intracanal bacteria . J Endod . 2002;28:779–783
  51. Siqueira J , Machado A , Silveira R , Lopes H , De Uzeda M . Evaluation of the effectiveness of sodium hypochlorite used with three irrigation methods in the elimination of Enterococcus faecalis from the root canal in vitro . Int Endod J . 1997;30:279–282
  52. Abdullah M , Ng YL , Gulabivala K , Moles DR , Spratt DA . Susceptibilties of two Enterococcus faecalis phenotypes to root canal medications . J Endod . 2005;31:30–36
  53. Torabinejad M , Shabahang S , Aprecio RM , Kettering JD . The antimicrobial effect of MTAD (an in vitro investigation) . J Endod . 2003;29:400–403
  54. Bystrom A , Sundqvist G . The antibacterial action of sodium hypochlorite and EDTA in 60 cases of endodontic therapy . Int Endod J . 1985;18:35–40
  55. Barroso Ldos S , Habitante SM , Jorge AO , Faria Ida S . Microorganisms growth in endodontic citric-acid solutions with and without microbiological stabilizer . J Endod . 2004;30:42–44
  56. Shabahang S , Torabinejad M . Effect of MTAD on Enterococcus faecalis - contaminated root canals of extracted human teeth . J Endod . 2003;29:576–579
  57. Torabinejad M , Cho Y , Khademi AA , Bakland LK , Shabahang S . The effect of various concentrations of sodium hypochlorite on the ability of MTAD to remove the smear layer . J Endod . 2003;29:233–239
  58. Safavi K , Spangberg L , Langeland K . Root canal dentinal tubule disinfection . J Endod . 1990;16:207–210
  59. Vahdaty A , Pitt Ford TR , Wilson RF . Efficacy of chlorhexidine in disinfecting dentinal tubules in vitro . Endod Dent Traumatol . 1993;9:243–248
  60. Gomes B , Souza S , Ferraz C , et al.   Effectiveness of 2% chlorhexidine gel and calcium hydroxide against Enterococcus faecalis in bovine root dentine in vitro . Int Endod J . 2003;36:267–275
  61. Basrani B , Santos J , Tjaderhane L , et al.   Substantive antimicrobial activity in chlorhexidine-treated human root dentin . Oral Surg Oral Med Oral Pathol Oral Radiol Endod . 2002;94:240–245
  62. White R , Hays G , Janer L . Residual antimicrobial activity after canal irrigation with chlorhexidine . J Endod . 1997;23:229–231
  63. Sassone L , Fidel R , Fidel S , Vieira M , Hirata R . The influence of organic load on the antimicrobial activity of different concentrations of NaOCl and chlorhexidine in vitro . Int Endod J . 2003;36:848–852
  64. Lynne RE , Liewehr FR , West LA , Patton WR , Buxton TB , McPherson JC . In vitro antimicrobial activity of various medication preparations on E. faecalis in root canal dentin . J Endod . 2003;29:187–190
  65. Evanov C , Liewehr F , Buxton TB , Joyce AP . Antibacterial efficacy of calcium hydroxide and chlorhexidine gluconate irrigants at 37 degrees C and 46 degrees C . J Endod . 2004;30:653–657
  66. Nagayoshi M , Kitamura C , Fukuizumi T , Nishihara T , Terashita M . Antimicrobial effect of ozonated water on bacteria invading dentinal tubules . J Endod . 2004;30:778–781
  67. Mickel AK , Sharma P , Chogle S . Effectiveness of stannous fluoride and calcium hydroxide against Enterococcus faecalis . J Endod . 2003;29:259–260
  68. Sukawat C , Srisuwan T . A comparison of the antimicrobial efficacy of three calcium hydroxide formulations on human dentin infected with Enterococcus faecalis . J Endod . 2002;28:102–104
  69. Cwikla SJ , Belanger M , Giguere S , Progulske-Fox A , Vertucci FJ . Dentinal tubule disinfection using three calcium hydroxide formulations . J Endod . 2005;31:50–52
  70. Evans MD , Baumgartner JC , Khemaleelakul SU , Xia T . Efficacy of calcium hydroxide (chlorhexidine paste as an intracanal medication in bovine dentin) . J Endod . 2003;29:338–339
  71. Shur A , Sedgley C , Fenno J . The antimicrobial efficacy of “MGP” gutta-percha in vitro . Int Endod J . 2003;36:616–621
  72. Lui J , Sae-Lim V , Song K , Chen N . In vitro antimicrobial effect of chlorhexidine-impregnated gutta percha points on Enterococcus faecalis . Int Endod J . 2004;37:105–113
  73. Lin S , Zuckerman O , Weiss EI , Mazor Y , Fuss Z . Antibacterial efficacy of a new chlorhexidine slow release device to disinfect dentinal tubules . J Endod . 2003;29:416–418
  74. Mickel A , Nguyen T , Chogle S . Antimicrobial activity of endodontic sealers on Enterococcus faecalis . J Endod . 2003;29:257–258
  75. Cobankara FK , Altinoz HC , Ergani O , Kav K , Belli S . In vitro antibacterial activities of root-canal sealers by using two different methods . J Endod . 2004;30:57–60
  76. Saleh I , Ruyter IE , Haapasalo M , Orstavik D . Survival of Enterococcus faecalis in infected dentinal tubules after root canal filling with different root canal sealers in vitro . Int Endod J . 2004;37:193–198
  77. Senia E , Marraro RV , Mitchell J , Lewis A , Thomas L . Rapid sterilization of gutta-percha cones with 5.25% sodium hypochlorite . J Endod . 1975;1:136–140
  78. Shipper G , Orstavik D , Teixeira F , Trope M . An evaluation of microbial leakage in roots filled with a thermoplastic synthetic polymer-based root canal filling material (Resilon) . J Endod . 2004;30:342–347
  79. Ray H , Trope M . Periapical status of endodontically treated teeth in relation to the technical quality of the root filling and the coronal restoration . Int Endod J . 1995;28:12–18

PII: S0099-2399(05)00093-2

doi: 10.1016/j.joen.2005.10.049

Journal of Endodontics
Volume 32, Issue 2 , Pages 93-98 , February 2006

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