Journal of Endodontics
Volume 26, Issue 10 , Pages 599-604 , October 2000

Molecular Epidemiology and Association of Putative Pathogens in Root Canal Infection

  • Il-Young Jung, DDS, MS

      Affiliations

    • Dr. Jung is a full-time lecturer, Department of Conservative Dentistry;, Seoul, Korea
    • Corresponding Author InformationAddress requests for reprints to Dr. Il-Young Jung, Department of Conservative Dentistry, Yonsei University, College of Dentistry, 134 Shinchon-Dong Seodaemun-Ku, Seoul, Korea
    • ,
  • Bong-kyu Choi, PhD

      Affiliations

    • Dr. Choi is a research fellow, Department of Oral Biology, Yonsei University, College of Dentistry, Seoul, Korea
    • ,
  • Ki-Yeon Kum, DDS, PhD

      Affiliations

    • Dr. Kum is an adjunct professor, Department of Conservative Dentistry;, Seoul, Korea
    • ,
  • Byoung-Duk Roh, DDS, PhD

      Affiliations

    • Dr. Roh is an adjunct professor, Department of Conservative Dentistry;, Seoul, Korea
    • ,
  • Seung-Jong Lee, DDS, PhD

      Affiliations

    • Dr. S-J Lee is a professor Department of Conservative Dentistry;, Seoul, Korea
    • ,
  • Chan-Young Lee, DDS, PhD

      Affiliations

    • Dr. C-Y. Lee is a professor, Department of Conservative Dentistry;, Seoul, Korea
    • ,
  • Dong-Soo Park, DDS, PhD

      Affiliations

    • Dr. Park is a professor, Department of Conservative Dentistry; Department of Conservative Dentistry;, Seoul, Korea

References 

  1. Woose CR . Bacterial evolution . Microbiol Rev . 1987;51:221–271
  2. Choi BK , Paster BJ , Dewhirst FE , Göbel UB . Diversity of cultivable and uncultivable oral spirochetes from a patient with severe destructive periodontitis . Infect Immun . 1994;62:1889–1895
  3. Conrads G , Gharbia SE , Lampert F , Shah HN . The use of a 16S rDNA directed PCR for the detection of endodontopathogenic bacteria . J Endodon . 1997;23:433–438
  4. Conrads G , Mutters R , Fisher J , Brauner A , Luetticken R , Lampert F . PCR reaction and dot-blot hybridization to monitor the distribution of oral pathogens within plaque samples of periodontally healthy individuals . J Periodontol . 1996;67:994–1003
  5. Loesche WJ , Lopatin DE , Stoll J , van Poperin N , Hujoel PP . Comparison of various detection methods for periodontopathic bacteria: can culture be considered the primary reference standard? . J Clin Microbiol . 1992;30:418–426
  6. Papapanou PN , Madianos PN , Dahlen G , Sandros J . “Checkerboard” versus culture: a comparison between two methods for identification of subgingival microbiota . Eur J Oral Sci . 1997;105:389–396
  7. Griffee MB , Patterson SS , Miller CH , Kafraway AH , Newton CW . The relationship of Bacteroides melaninogenicus to symptoms associated with pulpal necrosis . Oral Surg Oral Med Oral Pathol . 1980;50:457–461
  8. Sundqvist G , Johansson E , Sjögren U . Prevalence of black-pigmented Bacteroides species in root canal infections . J Endodon . 1989;15:13–19
  9. Haapasalo M . Bacteroides spp. in dental root canal infections . Endod Dent Traumatol . 1989;5:1–10
  10. Hashioka K , Yamasaki M , Nakane A , Horiba N , Nakamura H . The relationship between clinical symptoms and anaerobic bacteria from infected root canals . J Endodon . 1992;18:558–561
  11. Sundqvist G . Associations between microbial species in dental root canal infections . Oral Microbiol Immunol . 1992;7:257–262
  12. Baumgartner JC , Falkler WA , Beckerman T . Experimentally induced infection by oral anaerobic microorganisms in a mouse model . Oral Microbiol Immunol . 1992;7:253–256
  13. Gomes BPFA  , Drucker DB , Lilley JD . Positive and negative associations between bacterial species in dental root canals . Microbios . 1994;80:231–243
  14. Socransky SS , Haffajee AD , Dzink JL , Hillman JD . Associations between microbial species in subgingival plaque samples . Oral Microbiol Immunol . 1988;3:1–7
  15. Bae KS , Baumgartner JC , Shearer TR , David LL . Occurrence of Prevotella nigrescens and Prevotella intermedia in infections of endodontic origin . J Endodon . 1997;23:620–623
  16. Molven O , Olsen I , Kerekes K . Scanning electron microscopy of bacteria in the apical part of root canals in permanent teeth with periapical lesions . Endod Dent Traumatol . 1991;7:226–229
  17. Grenier D . Nutritional interactions between two suspected periodontopathogens, Treponema denticola and Porphyromonas gingivalis . Infect Immun . 1992;60:5298–5301
  18. Kesavalu L , Holt SC , Ebersole JL . Virulence of a polymicrobic complex, Treponema denticola and Porphyromonas gingivalis, in a murine model . Oral Microbiol Immunol . 1998;13:373–377
  19. Gharbia SE , Haapasalo M , Shah HN . Characterization of Prevotella intermedia and Prevotella nigrescens isolates from periodontic and endodontic infections . J Periodontol . 1994;65:56–61
  20. Hafström C , Dahlén G . Pathogenicity of Prevotella intermedia and Prevotella nigrescens isolates in a wound chamber model in rabbits . Oral Microbiol Immunol . 1987;12:148–154

 This work was supported (in part) by the Yonsei University Research Fund of 1998.

PII: S0099-2399(05)60892-8

doi: 10.1097/00004770-200010000-00006

Journal of Endodontics
Volume 26, Issue 10 , Pages 599-604 , October 2000

Article Tools