Lack of correlation between the amount of eugenol released from zinc oxide-eugenol sealer and cytotoxicity of the sealer

Maseki, Tomoharu; Nakata, Kazuhiko; Kohsaka, Toshiaki; Kobayashi, Fuminori; Hirano, Shinei; Nakamura, Hiroshi

doi:10.1016/S0099-2399(06)81612-2

« Previous Next »Journal of Endodontics
Volume 17, Issue 2 , Pages 76-79, February 1991

Lack of correlation between the amount of eugenol released from zinc oxide-eugenol sealer and cytotoxicity of the sealer

Tomoharu Maseki, DDS
- Address requests for reprints to Dr. Tomoharu Maseki, Department of Endodontics, School of Dentistry, Aichi-Gakuin University, 2–11 Suemoridori, Chikusa-ku, Nagoya 464 Japan.
- Drs. Maseki, Nakata, Kohsaka, Kobayashi, Hirano, and Nakamura are members of the Department of Endodontics, School of Dentistry, Aichi-Gakuin University
Kazuhiko Nakata, DDS
- Drs. Maseki, Nakata, Kohsaka, Kobayashi, Hirano, and Nakamura are members of the Department of Endodontics, School of Dentistry, Aichi-Gakuin University
Toshiaki Kohsaka, DDS
- Drs. Maseki, Nakata, Kohsaka, Kobayashi, Hirano, and Nakamura are members of the Department of Endodontics, School of Dentistry, Aichi-Gakuin University
Fuminori Kobayashi, DDS
- Drs. Maseki, Nakata, Kohsaka, Kobayashi, Hirano, and Nakamura are members of the Department of Endodontics, School of Dentistry, Aichi-Gakuin University
Shinei Hirano, DDS
- Drs. Maseki, Nakata, Kohsaka, Kobayashi, Hirano, and Nakamura are members of the Department of Endodontics, School of Dentistry, Aichi-Gakuin University
Hiroshi Nakamura, DDS, PhD
- Drs. Maseki, Nakata, Kohsaka, Kobayashi, Hirano, and Nakamura are members of the Department of Endodontics, School of Dentistry, Aichi-Gakuin University

The purpose of this study was to examine a possible correlation between the eugenol released from a zinc oxide-eugenol sealer (Canals) and the degree of cytotoxicity. The cytotoxicity and eugenol release from root canal filling material containing eugenol was examined for test solutions at several experimental periods. No positive correlation was found between eugenol release and cytotoxicity of the root canal filling material.

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