Journal of Endodontics
Volume 34, Issue 2 , Pages 181-185, February 2008

Evaluation of the Interaction between Sodium Hypochlorite and Chlorhexidine Gluconate and its Effect on Root Dentin

  • Tung B. Bui, DDS

      Affiliations

    • Department of Endodontology, Oregon Health & Science University, Portland, Oregon
    • Dr Bui is currently in private practice in Tucson, Az.
    • ,
  • J. Craig Baumgartner, DDS, PhD

      Affiliations

    • Department of Endodontology, Oregon Health & Science University, Portland, Oregon
    • Corresponding Author InformationAddress requests for reprints to J. Craig Baumgartner, DDS, PhD, Department of Endodontology, 611 SW Campus Dr, School of Dentistry, Oregon Health & Science University, Portland, OR 97239.
    • ,
  • John C. Mitchell, PhD

      Affiliations

    • Department of Biomaterials & Biomechanics, Oregon Health & Science University, Portland, Oregon.

Abstract 

The combination of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) forms a precipitate. The aim of this study was to evaluate the effect of irrigating root canals with a combination of NaOCl and CHX on root dentin and dentinal tubules by using the environmental scanning electron microscope (ESEM) and a computer program (Photoshop CS2). Forty-four extracted single-rooted human teeth were instrumented and irrigated with both NaOCl and CHX to produce a precipitate. Root canal surfaces were analyzed with the ESEM. The amount of remaining debris and number of patent tubules were determined. There were no significant differences in remaining debris between the negative control group and the experimental groups. There were significantly fewer patent tubules in the experimental groups when compared with the negative control group. The NaOCl/CHX precipitate tends to occlude the dentinal tubules. Until this precipitate is studied further, caution should be exercised when irrigating with NaOCl and CHX.

Key Words: Chlorhexidine, interaction of irrigants, precipitate, sodium hypochlorite

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PII: S0099-2399(07)00988-0

doi:10.1016/j.joen.2007.11.006

Journal of Endodontics
Volume 34, Issue 2 , Pages 181-185, February 2008

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