Journal of Endodontics
Volume 34, Issue 2 , Pages 181-185 , February 2008

Evaluation of the Interaction between Sodium Hypochlorite and Chlorhexidine Gluconate and its Effect on Root Dentin

  • Tung B. Bui, DDS

      Affiliations

    • Department of Endodontology, Oregon Health & Science University, Portland, Oregon
    • Dr Bui is currently in private practice in Tucson, Az.
    • ,
  • J. Craig Baumgartner, DDS, PhD

      Affiliations

    • Department of Endodontology, Oregon Health & Science University, Portland, Oregon
    • Corresponding Author InformationAddress requests for reprints to J. Craig Baumgartner, DDS, PhD, Department of Endodontology, 611 SW Campus Dr, School of Dentistry, Oregon Health & Science University, Portland, OR 97239.
    • ,
  • John C. Mitchell, PhD

      Affiliations

    • Department of Biomaterials & Biomechanics, Oregon Health & Science University, Portland, Oregon.

References 

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  5. Senia ES, Marshall FJ, Rosen S. The solvent action of sodium hypochlorite on pulp tissue of extracted teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1971;1:96–103
  6. Shih M, Marshall FJ, Rosen S. The bactericidal efficiency of sodium hypochlorite as an endodontic irrigant. Oral Surg Oral Med Oral Pathol. 1970;29:613–619
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  13. Dametto FR, Ferraz CC, de Almeida Gomes BP, Zaia AA, Teixeira FB, de Souza-Filho FJ. In vitro assessment of the immediate and prolonged antimicrobial action of chlorhexidine gel as an endodontic irrigant against Enterococcus faecalis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:768–772
  14. Kuruvilla JR, Kamath MP. Antimicrobial activity of 2.5% sodium hypochlorite and 0.2% chlorhexidine gluconate separately and combined, as endodontic irrigants. J Endod. 1998;24:472–476
  15. Gonzalex-Lopez S, Camejo-Aguilar D, Sanchez-Sanchez P, Polanos-Carmona V. Effect of CHX on the decalcifying effect of 10% citric acid, 20% citric acid, or 17% EDTA. J Endod. 2006;32:781–784
  16. Basrani BR, Manek S, Sodhi RNS, Fillery E, Manzur A. Interaction between sodium hypochlorite and chlorhexidine gluconate. J Endod. 2007;33:966–969
  17. Below H, Lehan N, Kramer A. HPLC determination of the antiseptic agent chlorhexidine and its degradation products 4-chloroaniline and 1-chloro-4-nitrobenzene in serum and urine. Microchimica Acta. 2004;146:129–135
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  21. Matsumoto M, Aiso S, Senoh H, et al. Carcinogenicity and chronic toxicity of para-chloronitrobenzene in rats and mice by two-year feeding. J Environ Pathol Toxicol Oncol. 2006;25:571–584
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PII: S0099-2399(07)00988-0

doi: 10.1016/j.joen.2007.11.006

Journal of Endodontics
Volume 34, Issue 2 , Pages 181-185 , February 2008

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