Journal of Endodontics
Volume 36, Issue 9 , Pages 1485-1489 , September 2010

Prevalence and Activity of Epstein-Barr Virus and Human Cytomegalovirus in Symptomatic and Asymptomatic Apical Periodontitis Lesions

  • Katinka Hernádi, MD

      Affiliations

    • Department of Medical Microbiology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    • ,
  • Anita Szalmás, MSc

      Affiliations

    • Department of Medical Microbiology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    • ,
  • Richárd Mogyorósi, MD

      Affiliations

    • Faculty of Dentistry, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    • ,
  • Levente Czompa, MD

      Affiliations

    • Faculty of Dentistry, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    • ,
  • György Veress, PhD

      Affiliations

    • Department of Medical Microbiology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    • ,
  • Eszter Csoma, PhD

      Affiliations

    • Department of Medical Microbiology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    • ,
  • Ildikó Márton, MD, PhD, DSci

      Affiliations

    • Faculty of Dentistry, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    • ,
  • József Kónya, MD, PhD

      Affiliations

    • Department of Medical Microbiology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    • Corresponding Author InformationAddress requests for reprints to Dr J Kónya, PO Box 17 Debrecen 4012 Hungary.

References 

  1. Sabeti M, Valles Y, Nowzari H, et al. Cytomegalovirus and Epstein-Barr virus DNA transcription in endodontic symptomatic lesions. Oral Microbiol Immunol. 2003;18:104–108
  2. Saygun I, Yapar M, Ozdemir A, et al. Human cytomegalovirus and Epstein-Barr virus type 1 in periodontal abscesses. Oral Microbiol Immunol. 2004;19:83–87
  3. Slots J, Contreras A. Herpesviruses: a unifying causative factor in periodontitis?. Oral Microbiol Immunol. 2000;15:277–280
  4. Sabeti M, Slots J. Herpesviral-bacterial coinfection in periapical pathosis. J Endod. 2004;30:69–72
  5. Sabeti M, Simon JH, Slots J. Cytomegalovirus and Epstein-Barr virus are associated with symptomatic periapical pathosis. Oral Microbiol Immunol. 2003;18:327–328
  6. Slots J, Sabeti M, Simon JH. Herpesviruses in periapical pathosis: an etiopathogenic relationship?. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;96:327–331
  7. Sabeti M, Simon JH, Nowzari H, et al. Cytomegalovirus and Epstein-Barr virus active infection in periapical lesions of teeth with intact crowns. J Endod. 2003;29:321–323
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  13. Sunde PT, Olsen I, Enersen M, et al. Human cytomegalovirus and Epstein-Barr virus in apical and marginal periodontitis: a role in pathology?. J Med Virol. 2008;80:1007–1011
  14. Chen V, Chen Y, Li H, et al. Herpesviruses in abscesses and cellulitis of endodontic origin. J Endod. 2009;35:182–188
  15. Kis A, Feher E, Gall T, et al. Epstein-Barr virus prevalence in oral squamous cell cancer and in potentially malignant oral disorders in an eastern Hungarian population. Eur J Oral Sci. 2009;117:536–540
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  17. Yazdi KA, Sabeti M, Jabalameli F, et al. Relationship between human cytomegalovirus transcription and symptomatic apical periodontitis in Iran. Oral Microbiol Immunol. 2008;23:510–514
  18. Saboia-Dantas CJ, Coutrin de Toledo LF, Sampaio-Filho HR, et al. Herpesviruses in asymptomatic apical periodontitis lesions: an immunohistochemical approach. Oral Microbiol Immunol. 2007;22:320–325
  19. Sahin S, Saygun I, Kubar A, et al. Periodontitis lesions are the main source of salivary cytomegalovirus. Oral Microbiol Immunol. 2009;24:340–342
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  24. Hahn CL, Liewehr FR. Innate immune responses of the dental pulp to caries. J Endod. 2007;33:643–651

PII: S0099-2399(10)00511-X

doi: 10.1016/j.joen.2010.06.008

Journal of Endodontics
Volume 36, Issue 9 , Pages 1485-1489 , September 2010

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