Abstract
This study compared the antimicrobial effect of MTAD, two of its components, doxycycline
and citric acid, and sodium hypochlorite (NaOCl) in two in vitro models on Enterococcus faecalis. In the bovine tooth model, the lumens of 30 bovine dentin discs were infected with
E. faecalis for 2 weeks before treating with either one of the experimental irrigants or saline.
Bacteria in the shavings were collected with two sizes of burs and enumerated after
overnight culturing. Zones of inhibition were recorded in the agar diffusion model
for each irrigant. In the tooth model, NaOCl and doxycycline were more effective than
control in killing E. faecalis at the shallow bur depth, but at the deeper bur depth only NaOCl was superior. In
the agar diffusion model, NaOCl produced less inhibition than MTAD or doxycycline.
Key Words
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Article info
Publication history
Published online: October 30, 2006
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© 2007 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
