Abstract
The purpose of this in vitro study was to investigate the antimicrobial action of
Dermacyn (Oculus Innovative Sciences, Petaluma, CA), BioPure MTAD (Dentsply Tulsa
Dental, Johnson City, TN), 2% chlorhexidine (CHX; Ultradent, West Jordan, UT), and
5.25% sodium hypochlorite (NaOCl) against Enterococcus faecalis (American Type Culture Collection 4082). Eighteen Petri dishes of BHI agar were inoculated
with E faecalis. Each Petri dish had five saturated paper disks placed. Four of the disks were saturated
with a different test solution, and the last paper disk served as the control and
was saturated with sterile distilled water. The plates were randomly distributed into
two groups. Group one (n = 9) was incubated aerobically and group 2 (n = 9) was incubated anaerobically for 48 hours at 37°C. The largest diameter of the
zones of microbial inhibition was measured in millimeters and recorded. Statistical
analysis was performed with repeated-measures analysis of variance. BioPure MTAD showed
significantly (p < 0.05) more zones of microbial inhibition than 5.25% NaOCl, 2% CHX,
and Dermacyn. Sodium hypochlorite and CHX showed significantly (p < 0.05) more zones
of microbial inhibition than Dermacyn. The zone of inhibition between NaOCl and CHX
was not significant (p > 0.05). The control group showed no microbial inhibition.
Key Words
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Article info
Publication history
Published online: March 31, 2007
Identification
Copyright
© 2007 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
