The quest for a scientific basis upon which to make clinical decisions is prominent
in our efforts to continually improve health care. Evidence-based dentistry, which
relies on a comprehensive, reliable and high quality body of science, offers valuable
guidance to the practice of endodontics. In evidence-based dentistry, published studies
are assigned a level of evidence (LOE), a relative ranking system that is based on
the potential impact of study design on resulting clinical implications. The highest
level of evidence comes from analyses of prospective, double blind, randomized controlled
clinical trials (RCT), the gold standard of science. The lowest level of evidence
is represented by the single clinical case report. In general, “bench top” or in vitro studies are rarely considered when developing LOE.
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References
- Levels of evidence for the outcome of endodontic retreatment.J Endod. 2004; 30: 745-750
- Levels of evidence for the outcome of endodontic surgery.J Endod. 2005; 31: 19-24
- Correlation between clinical success and apical dye penetration.Int Endod J. 2001; 34: 637-644
- Lack of correlation between ex vivo apical dye penetration and presence of apical radiolucencies.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006; 102: e19-e23
- Endodontic leakage studies reconsidered.Int Endod J. 1993; 26: 37-43
- Reliability of Apical Dye Sealability Studies with and without Vacuum Removal of Air Inclusions.([Thesis]) Baylor College of Dentistry, 1993
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© 2007 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
