Basic Research| Volume 37, ISSUE 1, P58-62, January 2011

Chemical Constitution, Physical Properties, and Biocompatibility of Experimentally Manufactured Portland Cement

Published:November 15, 2010DOI:



      An experimental Portland cement was manufactured with pure raw materials under controlled laboratory conditions. The aim of this study was to compare the chemical constitution, physical properties, and biocompatibility of experimentally manufactured Portland cement with those of mineral trioxide aggregate (MTA) and Portland cement.


      The composition of the cements was determined by scanning electron microscopy (SEM) and energy-dispersive x-ray analysis (EDAX). The setting time and compressive strength were tested. The biocompatibility was evaluated by using SEM and XTT assay.


      SEM and EDAX revealed the experimental Portland cement to have a similar composition to Portland cement. The setting time of the experimental Portland cement was significantly shorter than that of MTA and Portland cement. The compressive strength of the experimental Portland cement was lower than that of MTA and Portland cement. The experimental Portland cement showed a similar biocompatibility to MTA.


      The experimental Portland cement might be considered as a possible substitute for MTA in clinical usage after further testing.

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