Abstract
Introduction
The use of chelating agents in endodontic treatment is required to remove the smear
layer and to achieve better disinfection within the root canal system. The aim of
this study was to evaluate the residual antimicrobial activity of 17% ethylenediaminetetraacetic
acid (EDTA), 7% maleic acid (MA), and 10% lactic acid (LA) alone and combined with
0.2% cetrimide (CTR) on infected root canals with Enterococcus faecalis.
Methods
Biofilms of E. faecalis were grown in uniradicular roots for 4 weeks. After preparation the roots were randomly
divided into 6 groups (n = 15) according to the final irrigation regimen as follows:
5 mL of 17% EDTA; 5 mL of 17% EDTA + 0.2% CTR; 5 mL of 7% MA; 5 mL of 7% MA + 0.2%
CTR; 5 mL of 10% LA; and 5 mL of 10% LA + 0.2% CTR. Samples were collected for 60
days to denote the presence of bacterial growth. Fisher and Pearson χ2 tests were applied to compare the percentages of specimens without E. faecalis regrowth at all the time periods.
Results
There were significant differences in bacterial regrowth between the groups with and
without CTR. There were not significant differences over time among the 3 groups with
CTR or among the 3 without CTR.
Conclusions
The residual activity against E. faecalis of 7% MA + 0.2% CTR, 17% EDTA + 0.2% CTR, and 10% LA + 0.2% CTR was greater than
the use of chelating agents alone.
Key Words
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Article info
Publication history
Published online: February 27, 2012
Footnotes
Supported by the Research Group CTS-167 of the Junta de Andalucía, Spain.
Identification
Copyright
© 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
