Abstract
Introduction
In patients, the outcomes of teeth with necrotic pulps and open apexes that have been
treated with regenerative endodontics have always been evaluated clinically and radiographically.
The purpose of this case report is to present the clinical, radiographic, and histological
findings of a regenerative procedure using platelet-rich plasma (PRP) 14 months after
the procedure.
Methods
A 12-year-old boy whose maxillary second premolar tooth had been treated with regenerative
endodontics was seen with a chief complaint of pain and sensitivity to cold. After
clinical and radiographic examinations, a pulpal diagnosis of reversible pulpitis
and normal periapical tissues was made for this tooth. Because of the patient’s complaint
and his guardian’s insistence on either a root canal treatment or an extraction, a
root canal treatment was performed in this tooth. After entry into the root canal,
the soft tissue present in the canal was removed with the aid of a large barbed broach
and examined histologically.
Results
Examination of the tissue removed from the root canal of this tooth revealed the presence
of a vital pulp-like vital connective tissue. There was no evidence of bone in the
specimen. Very few inflammatory cells were noted in the periphery of the specimen.
Conclusions
Based on these findings, it appears that pulp-like tissue can be generated in a human
tooth with the use of PRP as a scaffold in regenerative endodontic procedures.
Key Words
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© 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
