Abstract
Introduction
The objective of this study was to investigate the association between chronic apical
periodontitis (CAP) and low-birth-weight preterm births (LBWPB).
Methods
Sixty-three women in postpartum period were included in this case-control study. The
case group consisted of mothers of LBWPB infants (n = 33), and the control group was represented by mothers of newborns at term (n = 30). The CAP diagnosis was performed by using periapical radiographs through the
periapical index in postpartum period. The χ2 test, Fisher exact test, and linear and logistic regression were used for statistical
analysis.
Results
It was observed that CAP was present in 54.5% of mothers in the case group and 20.0%
in the control group (P = .004); postpartum women with CAP had about 3.5 times greater odds of LBWPB newborns
than women without CAP (adjusted odds ratio, 3.52; 95% confidence interval, 1.01–12.32).
Postpartum women who reported 6 or more prenatal consultations reduced odds of LBWPB
newborns in 80% (adjusted odds ratio, 0.20; 95% CI, 0.06–0.69). It can be estimated
that the increase of 1 unit of periapical index had a significant association with
the reduction of 1½ gestational weeks in the crude analysis (β = –1.5, P = .010) and the reduction of 211 g in birth weight after the adjusted analysis (β
= –211, P = .058).
Conclusions
Prematurity and low birth weight were associated with radiographically detected CAP.
Women with CAP in postpartum period had greater odds of LBWPB.
Key Words
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References
- Clinical implications and microbiology of bacterial persistence after treatment procedures.J Endod. 2008; 34: 1291-1301
- Lesions of endodontic origin and risk of coronary heart disease.J Dent Res. 2006; 85: 996-1000
- Bacteria in the apical root canal of teeth with primary apical periodontitis.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 107: 721-726
- Genetic predisposition to persistent apical periodontitis.J Endod. 2011; 37: 455-459
- Can apical periodontitis modify systemic levels of inflammatory markers? a systematic review and meta-analysis.J Endod. 2013; 39: 1205-1217
- Immunoexpression of interleukin 17 in apical periodontitis lesions.J Endod. 2014; 40: 1400-1403
- Endodontic treatment and prevalence of apical periodontitis in an adult population of Vilnius, Lithuania.Dent Traumatol. 1999; 15: 210-215
- Risk indicators for apical periodontitis.Community Dent Oral Epidemiol. 2003; 31: 59-67
- Radiographic study of the prevalence of periapical periodontitis and endodontic treatment in the adult population of São Luís, MA, Brazil.J Appl Oral Sci. 2006; 14: 183-187
- Periapical health related to the quality of root canal treatment in Belgian population.Int Endod J. 2000; 33: 113-120
- Prevalence of apical periodontitis and results of endodontic treatment in adult, Portuguese population.Int Endod J. 1998; 31: 161-165
- Prevalence and quality of endodontic treatment in an urban adult population in Norway.Dent Traumatol. 1988; 4: 122-126
- Periapical status and prevalence of endodontic treatment in an adult Dutch population.Int Endod J. 1993; 26: 112-119
- Prevalence of periapical radiolucency and root canal treatment: a systematic review of cross-sectional studies.J Endod. 2012; 38: 1170-1176
- The outcome of endodontic treatment: a retrospective study of 2000 cases performed by a specialist.J Endod. 2007; 33: 1278-1282
- Prevalence of apical periodontitis of root canal–treated teeth and retrospective evaluation of symptom-related prognostic factors in an urban South Korean population.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010; 110: 795-799
- Periodontal infection as possible risk factor for preterm low birth weight.J Periodontol. 1996; 67: 1103-1113
- Potential pathogenic mechanism of periodontitis associated pregnancy complications.Ann Periodontol. 1998; 3: 233-250
- Periodontal disease and preterm delivery of low-birth-weight infants.J Can Dent Assoc. 2002; 68: 165-169
- Women with a recent history of early onset pre eclampsia have a worse periodontal condition.J Clin Periodontol. 2007; 34: 202-207
- Periodontal disease and perinatal outcomes: a case control study.J Clin Periodontol. 2007; 34: 31-39
- Maternal periodontal disease and preterm or extreme preterm birth: an ordinal logistic regression analysis.J Periodontol. 2010; 81: 350-358
- Association of maternal periodontal health with adverse pregnancy outcome.J Obstet Gynaecol Res. 2013; 39: 40-45
- Epidemiology of association between maternal periodontal disease and adverse pregnancy outcomes: systematic review.J Clin Periodontol. 2013; 40: S181-S194
- Ecology of the root canal flora.J Endod. 1992; 18: 427-430
- The localization of periodontal-disease-associated bacteria in human periodontal pockets.J Dent Res. 2001; 80: 1930-1934
- Detection of interleukin-6 in human dental pulp and periapical lesions.Dent Traumatol. 1999; 15: 26-27
- Levels of interleukin-1β, -8, and -10 and RANTES in gingival crevicular fluid and cell populations in adult periodontitis patients and the effect of periodontal treatment.J Periodontol. 2000; 71: 1535-1545
- Diabetes mellitus, periapical inflammation and endodontic treatment outcome.Med Oral Patol Oral Cir Bucal. 2012; 17: e356
- Type 2 diabetes mellitus and the prevalence of apical periodontitis and endodontic treatment in an adult Brazilian population.J Endod. 2012; 38: 297-300
- Blood profile and histology in oral infections associated with diabetes.J Endod. 2014; 40: 1139-1144
- Association between chronic dental infection and acute myocardial infarction.J Endod. 2009; 35: 626-630
- Infectious dental diseases in patients with coronary artery disease: an orthopantomographic case-control study.J Can Dent Assoc. 2009; 75: 35
- Association among oral health, apical periodontitis, CD14 polymorphisms, and coronary heart disease in middle-aged adults.J Endod. 2012; 38: 1570-1577
- Tobacco smoking and radiographic periapical status: a retrospective case-control study.J Endod. 2012; 38: 584-588
- The periapical index: a scoring system for radiographic assessment of apical periodontitis.Dent Traumatol. 1986; 2: 20-34
- Radiological diagnosis of periapical bone tissue lesions in endodontics: a systematic review.Int Endod J. 2012; 45: 783-801
- Radiographic follow-up of periapical status after endodontic treatment of teeth with and without apical periodontitis.Clin Oral Investig. 2013; 17: 2099-2104
- Periapical status of root-filled teeth in Norwegian children and adolescents.Acta Odontol Scand. 2014; 72: 801-805
Article info
Publication history
Published online: January 06, 2015
Identification
Copyright
© 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
