Abstract
Introduction
This study aimed to evaluate the impact of preoperative pulp inflammation on the histologic
outcome of full pulpotomy performed in mature permanent posterior teeth using 4 different
biomaterials.
Methods
Five beagle dogs (providing a total of 120 roots) were selected. Dentin exposure was
performed in teeth from the second and third quadrants. One week later, full pulpotomy
procedures were performed using 4 different bioactive materials (ProRoot MTA [MTA],
TotalFill BC Putty [BC], Biodentine [BIO], and an experimental cement [ie, pulp capping
material]). The hemostasis time was registered. After 14 weeks, the animals were killed.
Pulp-dentin tissues were histologically and radiographically assessed. The significance
level was set at .05.
Results
Teeth with previously exposed dentin revealed a statistically significant increase
in the time required to achieve hemostasis (P < .001), therefore confirming the pulp inflammation status induced by 1-week exposure
of occlusal dentin before performing full pulpotomy. There was no radiographic evidence
of root resorption, periapical radiolucency, or lamina dura alterations. No statistically
significant differences were observed between normal and inflamed pulp regardless
of the evaluated histologic parameters. Moreover, histologic data concerning calcified
barrier formation and the pulp tissue response show better results for BIO without
statistical differences compared with MTA or BC (P > .05). The pulp capping material presented a lower performance, with statistically
significant differences being detected in regard to the remaining 3 tested materials
(P < .001).
Conclusions
Radiographic and histologic outcomes of full pulpotomy are not jeopardized by short-term
preoperative pulp inflammation. Moreover, BIO, MTA, and BC cements present suitable
alternatives to be used as pulp capping agents.
Key Words
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Article info
Publication history
Published online: July 02, 2021
Identification
Copyright
© 2021 American Association of Endodontists.
