Abstract
Introduction
The purpose of this study was to compare clinically and radiographically the effects
of potassium nitrate in polycarboxylate cement and mineral trioxide aggregate (MTA)
as pulpotomy agents in vital immature mandibular first molars.
Methods
The trial design was a parallel randomized, 1:1 allocation ratio, with both the participants
and the data assessor blinded. A total of 50 molars of 48 eligible children aged 6–9 years
were studied. The children had mandibular immature first molars with extensive caries
that revealed pulp exposure during caries excavation. Patients were randomly allocated
equally into 2 groups in which potassium nitrate in polycarboxylate cement (the intervention
group) and MTA (the control group) were used as pulpotomy biomaterials. The treated
teeth were restored permanently. The primary outcome was clinical/radiographic assessment
after 1 week, 6 months, and 12 months. The secondary outcomes were radiometric analysis
at 6 and 12 months to determine dimensional changes during maturogenesis. The digital
radiographs were imported to image processing software to perform radiometric measurements.
Data were tabulated and statistically analyzed with significance set at P ≤ .05.
Results
Only a single tooth failed at the 6-month recall, and another one was lost during
recall in each group. Thus, the overall success rate for cases/group who finally attended
the 12-month follow-up time point was 92% (23/25) with no statistically significant
difference between the 2 groups. At the 12-month recall, successful cases showed root
development with an increase in root length and a decrease in apical foramen width.
Complete apical closure was observed in 65.2% of the roots in the intervention group
and 52.1% in the control group.
Conclusions
The clinical and radiographic success reported in the present study reveals that potassium
nitrate in polycarboxylate cement could be used as a biological and economic alternative
to MTA as a pulpotomy agent in vital immature mandibular first molars. Further follow-up
for longer periods is recommended.
Key Words
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Article info
Publication history
Published online: August 31, 2021
Identification
Copyright
© 2021 Published by Elsevier Inc. on behalf of American Association of Endodontists.
