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Association between single nucleotide polymorphisms in candidate genes and success of pulpal anesthesia following inferior alveolar nerve block

  • E. Karataş
    Correspondence
    Address for correspondence/reprints: Ertuğrul Karataş, Department of Endodontics, Faculty of Dentistry, Ataturk University, Erzurum, 25240, Turkey, Business telephone number: +90.442.231 3804. Fax number: +90.442.231 2270.
    Affiliations
    Department of Endodontics, Faculty of Dentistry and Department of Medical Genetics, Medical Faculty, Atatürk University, Erzurum, Turkey
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  • M. Sümbüllü
    Affiliations
    Department of Endodontics, Faculty of Dentistry and Department of Medical Genetics, Medical Faculty, Atatürk University, Erzurum, Turkey
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  • Ç.Y. Kahraman
    Affiliations
    Department of Endodontics, Faculty of Dentistry and Department of Medical Genetics, Medical Faculty, Atatürk University, Erzurum, Turkey
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  • F.A. Çakmak
    Affiliations
    Department of Endodontics, Faculty of Dentistry and Department of Medical Genetics, Medical Faculty, Atatürk University, Erzurum, Turkey
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Published:October 27, 2022DOI:https://doi.org/10.1016/j.joen.2022.09.004
      A successful pulpal anesthesia is essential to reduce the fear and anxiety of the patient and to ensure patients’ comfort during endodontic treatment (
      • Khan A.A.
      • Owatz C.B.
      • Schindler W.G.
      • Schwartz S.A.
      • Keiser K.
      • Hargreaves K.M.
      Measurement of mechanical allodynia and local anesthetic efficacy in patients with irreversible pulpitis and acute periradicular periodontitis.
      ). However, it is not always possible to achieve adequate pulpal anesthesia, especially in mandibular molars with symptomatic irreversible pulpitis (SIP) (
      • Dianat O.
      • Mozayeni M.A.
      • Layeghnejad M.K.
      • Shojaeian S.
      The efficacy of supplemental intraseptal and buccal infiltration anesthesia in mandibular molars of patients with symptomatic irreversible pulpitis.
      ).

      Keywords

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