Abstract
Introduction
The overall prevalence of maxillary sinusitis of odontogenic origin (MSOO) is still
unknown. Therefore, this study aimed to determine the pooled prevalence of MSOO and
verify associations between different odontogenic conditions and MSOO.
Methods
Six electronic databases and the gray literature were searched on August 25, 2022.
Two independent reviewers selected observational studies reporting the prevalence
of MSOO and associated conditions in adults. Studies that did not use computed tomography
for diagnosis were excluded. The methodological quality of the studies was assessed
using the Joanna Briggs Institute Critical Appraisal Checklist for Cross-Sectional
Studies. Data were analyzed by proportion and association meta-analyses. The certainty
of evidence was assessed using the Grading of Recommendations Assessment, Development
and Evaluation approach.
Results
Thirty-eight studies were included in the qualitative analysis and thirty-one in the
meta-analyses. Only 12 studies (31.6%) fulfilled all items of the methodological quality
checklist. Overall, the studies reported prevalence measures per maxillary sinus or
patient. Thus, the pooled prevalence of MSOO was 51% per sinus (95% confidence interval
[CI] [40%–61%]) and 50% per patient (95% CI [41%–59%]). Apical lesion (odds ratio
[OR]: 4.03, 95% CI [2.26–7.19]), periodontitis (OR: 5.49, 95% CI [2.27–13.24]), moderate
(OR: 2.57, 95% CI [1.85–3.57]) and severe bone loss (OR: 13.80, 95% CI [2.81–67.85]
were significantly associated with MSOO. The certainty of the evidence for the associations
was very low.
Conclusions
The pooled prevalence of MSOO on computed tomography assessment was 51% per maxillary
sinus and 50% per patient. Therefore, half of the maxillary sinusitis may be of odontogenic
origin. Apical lesion, periodontitis, and moderate and severe bone loss were significantly
associated with MSOO.
Key Words
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Article info
Publication history
Published online: February 06, 2023
Identification
Copyright
© 2023 American Association of Endodontists.
