Abstract
The purpose of this case report was to inform dentists and dental specialists about
a noninvasive, viable treatment option that could aid in the recovery of patients
who have experienced iatrogenic nerve injuries. Nerve injury is an inherent risk of
many dental procedures and a complication that can negatively impact a patient’s quality
of life and activities of daily living. Managing neural injuries presents a challenge
for clinicians because there are no standard protocols reported in the literature.
Although spontaneous healing of these injuries can occur, the duration and degree
of healing can vary greatly between individuals. Photobiomodulation (PBM) therapy
is used as an adjunct in medicine for functional nerve recovery. Once target tissues
are illuminated with a low-level laser during PBM, the light energy is absorbed by
the mitochondria causing adenosine triphosphate production, modulation of reactive
oxygen species, and the release of nitric oxide. These cellular changes explain why
PBM has been shown to aid in cell repair, vasodilation, a reduction in inflammation,
accelerated healing, and an improvement in postoperative pain. This case report presents
2 patients with neurosensory alterations after endodontic microsurgery with a significant
improvement in their condition after PBM treatment using a 940-nm diode laser.
Key Words
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References
- Incidence of altered sensation after mandibular premolar and molar periapical surgery.J Endod. 2020; 46: 29-33
- Endodontics and neurovascular injury endodontics: colleagues for excellence 2021.Fall. 2021; : 1-8
- International Association for the Study of Pain Terminology Pain.2011
- The prognosis of altered sensation after extrusion of root canal filling materials: a systematic review of the literature.J Endod. 2016; 42: 873-879
- Developments in low level light therapy (LLLT) for dentistry.Dent Mater. 2014; 30: 465-475
- Laser photobiomodulation of proliferation of cells in culture: a review of human and animal studies.Photomed Laser Surg. 2010; 28: S3-S40
- Mitochondrial signaling in mammalian cells activated by red and near-IR radiation.J Photochem Photobiol. 2008; 84: 1091-1099
- Effect of low-level laser therapy on postoperative pain after root canal retreatment: a preliminary placebo-controlled, triple-blind, randomized clinical trial.J Endod. 2017; 43: 1765-1769
- Effect of low-level laser therapy on postoperative pain in molars with symptomatic apical periodontitis: a randomized placebo-controlled clinical trial.J Endod. 2018; 44: 1610-1615
- Use of a 660-nm laser to aid in the healing of necrotic alveolar mucosa caused by extruded sodium hypochlorite: a case report.J Endod. 2015; 41: 1899-1902
- Cytotoxic, migration, and angiogenic effects of photodynamic therapy and photobiomodulation associated with a revascularization protocol.J Endod. 2021; 47: 69-77
- Sensory testing of inferior alveolar nerve injuries: a review of methods used in prospective studies.J Oral Maxillofac Surg. 2009; 67: 292-300
- Avoiding the mental foramen during periapical surgery.J Endod. 1995; 21: 340-342
- Nerve injuries after dental injection: a review of the literature.J Can Dent Assoc. 2006; 72: 559-564
- Neuropathy of trigeminal nerve branches after oral and maxillofacial treatment.J Maxillofac Surg. 2016; 15: 321-327
- Neurosensory disturbances after apical surgery of mandibular premolars and molars: a retrospective analysis and case-control study.EUR Endod J. 2021; 6: 247-253
- Low-Level Light Therapy for Nerve and Spinal Cord Regeneration Handbook of Photomedicine.1st ed. 2013: 669-676
- Efficacy of low-level laser therapy in nerve injury repair-a new era in therapeutic agents and regenerative treatments.Neurol Sci. 2021; 42: 4029-4043
- Current status of therapeutic approaches against peripheral nerve injuries: a detailed story from injury to recovery.Int J Biol Sci. 2020; 16: 116-134
- Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.J Neuroinflammation. 2021; 18: 256
- The effect of delayed photobiomodulation on neurosensory disturbance recovery after zygomatic trauma: a parallel controlled clinical trial.J Photochem Photobiol B. 2021; 217: 112153
- Use of 1064 nm Nd:YAG laser biostimulation for immediate reversal of a long-standing paresthesia of the superior labial branch of the infraorbital nerve following a root coverage procedure: a case report.Clin Adv Periodontics. 2021; 11: 93-97
- Do corticosteroids still have a role in the management of third molar surgery?.Advances in therapy. 2016; 33: 1105-1139
- Efficacy of steroid treatment for sensory impairment after orthognathic surgery.J Maxillofac Surg. 2004; 62: 1193-1197
- Stress-strain phenomena in human peripheral nerve trunks.Brain (London, England: 1878). 1961; 84: 102-119
- Anatomical relationship between mental foramen, mandibular teeth and risk of nerve injury with endodontic treatment.Clin Oral Investig. 2017; 21: 381-387
- Effects of superpulsed, low-level laser therapy on neurosensory recovery of the inferior alveolar nerve.J Craniofac Surg. 2016; 27: 1215-1219
Article info
Publication history
Published online: March 07, 2023
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2023 American Association of Endodontists.